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Test Code ADULT Adulterants Survey, Random, Urine

Useful For

Assessment of possible adulteration of a urine specimen submitted for drug of abuse testing

 

Providing the creatinine concentration for normalization purposes

Testing Algorithm

For more information see Adulterant Survey Algorithm.

Special Instructions

Reporting Name

Adulterants Survey, U

Specimen Type

Urine


Ordering Guidance


For situations where chain of custody is required, a Chain-of-Custody Kit (T282) is available. For chain-of-custody information, see ADLTX / Adulterants Survey, Chain of Custody, Random, Urine.



Specimen Required


Container/Tube: Plastic, 60-mL urine bottle

Specimen Volume: 1.5 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative.

Additional Information: Submitting less than 1.5 mL may compromise the ability to perform all necessary testing.


Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 14 days
  Frozen  14 days
  Ambient  72 hours

Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Clinical Information

Specimen adulteration is the manipulation of a sample that may cause false-negative test results for the presence of drugs of abuse. Common adulterants that may affect testing are water, soap, bleach, vinegar, oxidants, and salt. The adulteration testing includes assessment of creatinine concentration, pH, urine specific gravity, presence or absence of an oxidant, and presence or absence of nitrite.

Interpretation

For information see Adulterant Survey Algorithm.

Method Description

All results are measured using spectrophotometry at wavelengths specified by the reagent manufacturer. The use of a refractometer may also be used in the specific gravity measurement.(Package inserts: Specimen Validity Test Creatinine. Roche Diagnostics; V3.0, 08/2015; Specimen Validity Test Nitrite. Roche Diagnostics; V3.0, 08/2018, Specimen Validity Test Oxidant. Roche Diagnostics; V 3.0, 08/2018; Specimen Validity Test pH Roche Diagnostics; V3.0, 02/2019, Specimen Validity Test Specific Gravity. Roche Diagnostics; V4.0, 08/2022)

Day(s) Performed

Monday through Saturday

Performing Laboratory

Mayo Clinic Laboratories in Rochester

LOINC Code Information

Test ID Test Order Name Order LOINC Value
ADULT Adulterants Survey, U 58714-7

 

Result ID Test Result Name Result LOINC Value
20606 Creatinine, U 2161-8
22312 Specific Gravity 5810-7
23509 pH 2756-5
23511 Oxidants 58714-7
23510 Nitrites 32710-6
30914 Comment 48767-8

Method Name

Spectrophotometry (SP)

Reference Values

Cutoff concentrations

Oxidants: 200 mg/L

Nitrites: 500 mg/L

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

Secondary ID

29345

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.