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HelpTest Code FHPL Human Placental Lactogen (HPL)
Specimen Required
Specimen Type: Serum
Container/Tube: Red Top
Specimen Volume: 1 mL
Collection Instructions: Draw blood in a red top tube(s). Separate and send 1 mL of serum frozen.
Method Name
Enzyme-Linked Immunosorbent Assay (ELISA)
Reporting Name
Human Placental LactogenSpecimen Type
Serum RedSpecimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum Red | Frozen | 90 days |
Reject Due To
| List other reasons for rejection | Specimens other than serum. |
Reference Values
Males and nonpregnant Woman: 0.00 - 0.10 mcg/mL
1st Trimester of Pregnancy: 0.20 - 2.10 mcg/mL
2nd Trimester of Pregnancy: 0.50 - 6.70 mcg/mL
3rd Trimester of Pregnancy: 4.50 - 12.80 mcg/mL
Day(s) Performed
Thursday
Performing Laboratory
BioAgilytix DiagnosticsTest Classification
The performance characteristics of the listed assay was validated by BioAgilytix Diagnostics. The US FDA has not approved or cleared this test. The results of this assay can be used for clinical diagnosis without FDA approval. BioAgilytix Diagnostics is a CLIA certified, CAP accredited laboratory for performing high complexity assays such as this one.CPT Code Information
83632
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| FHPL | Human Placental Lactogen | 2104-8 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| Z0146 | Human Placental Lactogen | 2104-8 |
Clinical Information
Human placental lactogen (hPL; chorionic somatomammotropin) is a 21,000 KD polypeptide produced during pregnancy by placental trophoblastic cells. The level of hPL in maternal serum is directly related to placental function and fetal well-being.
hPL is detected at about 6 weeks after conception and its concentration increases gradually to peak levels (without decreases) until about the 34th week where it remains stable for the remainder of the pregnancy. Consistently low levels throughout pregnancy or a sudden drop in serial determinations are an indication of fetal distress. After normal delivery, the hPL concentration falls rapidly to an undetectable level.
The hPL levels in serum of women with multiple placenta pregnancies generally exceeds that of single placenta pregnancies. This is generally noted from the 2nd trimester to delivery.