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Test Code FPAB Vitamin B5 (Pantothenic Acid) Bioassay


Specimen Required


Specimen Type: Serum

Container/Tube: SST

Specimen Volume: 2 mL

Collection Instructions: Draw blood in SST (serum separator tube). Allow sample to clot for 30 minutes at room temperature. Spin down and send 1 mL serum frozen in an amber vial (T915) to protect from light.


Method Name

Microbiological Assay

Reporting Name

Pantothenic Acid (B-5) Bioassay

Specimen Type

Serum SST

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum SST Frozen (preferred) 21 days LIGHT PROTECTED
  Refrigerated  7 days LIGHT PROTECTED

Reject Due To

Gross hemolysis: Reject
Thawing: Warm Reject; Cold OK
Gross lipemia: Reject
List other reasons for rejection: Reject specimens containing particulate matter or microbial contamination. Specimens unprotected from light.

Reference Values

Adult Reference Range

>10 Years                     37-147 ug/L

 

Pediatric Reference Range

≤1 Year                 3.45 to 825 ug/L

>1 year to 10 Years       3.45 to 229.2 ug/L

 

Day(s) Performed

Monday

Performing Laboratory

BioAgilytix Diagnostics

Test Classification

The performance characteristics of the listed assay was validated by BioAgilytix Diagnostics. The US FDA has not approved or cleared this test. The results of this assay can be used for clinical diagnosis without FDA approval. BioAgilytix Diagnostics is a CLIA certified, CAP accredited laboratory for performing high complexity assays such as this one.

CPT Code Information

84591

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FPAB Pantothenic Acid (B-5) Bioassay 2722-7

 

Result ID Test Result Name Result LOINC Value
FPAB Pantothenic Acid (B-5) Bioassay 2722-7

Clinical Information

Pantothenic acid, commonly known as vitamin B5, is a water-soluble vitamin. As part of acetyl CoA or an acyl carrier protein, pantothenic acid plays an essential role in metabolic pathways. It functions in the oxidation of both fatty acids and carbohydrates for energy production in the form of A TP. Vitamin B5 also participates in the synthesis of amino acids, fatty acids, ketones, cholesterol, phospholipids, and steroids. Additionally, vitamin B5 contributes to porphyrin and hemoglobin biochemistry and in adrenal function. Pantothenic acid deficiency is exceedingly rare, mostly affecting individuals who are severely malnourished. Those who lack an adequate amount of vitamin B5 may demonstrate symptoms such as paresthesias, muscle weakness, fatigue, nausea, abdominal pains and susceptibility to infection.